aav php eb capsids Search Results


aav-php.eb  (VectorBuilder GmbH)
90
VectorBuilder GmbH aav-php.eb
Aav Php.Eb, supplied by VectorBuilder GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aav-php.eb - by Bioz Stars, 2026-05
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aav-php.eb viruses  (PackGene Biotech lnc)
90
PackGene Biotech lnc aav-php.eb viruses
Aav Php.Eb Viruses, supplied by PackGene Biotech lnc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aav-php.eb viruses - by Bioz Stars, 2026-05
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aav-php.eb-syn-mscarlet-p2a-mcs rep-cap trans plasmid  (GenScript corporation)
90
GenScript corporation aav-php.eb-syn-mscarlet-p2a-mcs rep-cap trans plasmid
Aav Php.Eb Syn Mscarlet P2a Mcs Rep Cap Trans Plasmid, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aav-php.eb-syn-mscarlet-p2a-mcs rep-cap trans plasmid - by Bioz Stars, 2026-05
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aav-php.eb vectors expressing the sacas9 and the selected sgrna  (SignaGen)
90
SignaGen aav-php.eb vectors expressing the sacas9 and the selected sgrna
Aav Php.Eb Vectors Expressing The Sacas9 And The Selected Sgrna, supplied by SignaGen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aav-php.eb vectors expressing the sacas9 and the selected sgrna - by Bioz Stars, 2026-05
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aav.php.eb-syn-l10a-egfp  (SignaGen)
90
SignaGen aav.php.eb-syn-l10a-egfp
Aav.Php.Eb Syn L10a Egfp, supplied by SignaGen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aav.php.eb-syn-l10a-egfp/product/SignaGen
Average 90 stars, based on 1 article reviews
aav.php.eb-syn-l10a-egfp - by Bioz Stars, 2026-05
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aav vectors containing aav/php.s capsids  (Harvard Bioscience)
90
Harvard Bioscience aav vectors containing aav/php.s capsids
Aav Vectors Containing Aav/Php.S Capsids, supplied by Harvard Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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aav-php.eb-cag- hlgmn vector  (SignaGen)
90
SignaGen aav-php.eb-cag- hlgmn vector
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Php.Eb Cag Hlgmn Vector, supplied by SignaGen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aav-php.eb-cag- hlgmn vector/product/SignaGen
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aav-php.eb-cag- hlgmn vector - by Bioz Stars, 2026-05
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aav ultra-purified cre-dependent aav-flexon-shrnas (shcontrol or shmyh9 + shactg1)-egfp php.eb serotype viruses  (VectorBuilder GmbH)
90
VectorBuilder GmbH aav ultra-purified cre-dependent aav-flexon-shrnas (shcontrol or shmyh9 + shactg1)-egfp php.eb serotype viruses
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Ultra Purified Cre Dependent Aav Flexon Shrnas (Shcontrol Or Shmyh9 + Shactg1) Egfp Php.Eb Serotype Viruses, supplied by VectorBuilder GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aav ultra-purified cre-dependent aav-flexon-shrnas (shcontrol or shmyh9 + shactg1)-egfp php.eb serotype viruses - by Bioz Stars, 2026-05
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aav-php.eb vectors  (Excellgene sa)
90
Excellgene sa aav-php.eb vectors
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Php.Eb Vectors, supplied by Excellgene sa, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
aav-php.eb vectors - by Bioz Stars, 2026-05
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aav-php.eb  (Genlantis inc)
90
Genlantis inc aav-php.eb
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Php.Eb, supplied by Genlantis inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aav-php.eb/product/Genlantis inc
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aav-php.eb - by Bioz Stars, 2026-05
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aav-php.eb-cag>kozak-egfp-ggaaga repeat (gr∗30)  (Cyagen Biosciences)
90
Cyagen Biosciences aav-php.eb-cag>kozak-egfp-ggaaga repeat (gr∗30)
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Php.Eb Cag>Kozak Egfp Ggaaga Repeat (Gr∗30), supplied by Cyagen Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aav-php.eb-cag>kozak-egfp-ggaaga repeat (gr∗30)/product/Cyagen Biosciences
Average 90 stars, based on 1 article reviews
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aav-php.eb-hsyn-satb2-3ha-2a-gfp  (PackGene Biotech lnc)
90
PackGene Biotech lnc aav-php.eb-hsyn-satb2-3ha-2a-gfp
a , Representative immunoblots for total LGMN and human LGMN <t>(hLGMN)</t> in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate <t>of</t> <t>AAV-injected</t> Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).
Aav Php.Eb Hsyn Satb2 3ha 2a Gfp, supplied by PackGene Biotech lnc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


a , Representative immunoblots for total LGMN and human LGMN (hLGMN) in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate of AAV-injected Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).

Journal: bioRxiv

Article Title: Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

doi: 10.1101/2024.01.16.575687

Figure Lengend Snippet: a , Representative immunoblots for total LGMN and human LGMN (hLGMN) in total brain homogenate (NP40) of Grn KO mice, three months p.i. and age-matched non-injected controls, GAPDH verified equal loading. LGMN expression is quantified and normalized to Grn ko (n=3 mice per condition, mean ± s.d) b , In vitro LGMN activity assay of total brain homogenate of AAV-injected Grn ko mice and age-matched non-injected controls (n=6 mice per condition, mean ± s.d). c , Representative immunoblot of TDP-43 in the RIPA soluble fraction of total brain lysates and pTDP-43 in the urea-soluble fraction, GAPDH verified equal loading. For quantification of TDP-43 processing in the RIPA fraction, the signal of indicated TDP-43 fragments was normalized to the total TDP-43 signal (n=6 mice per condition, mean ± s.d., multiple t-tests with FDR correction). pTDP-43 accumulation in the urea fraction was quantified and normalized to Grn ko (n=6 mice per condition, mean ± s.d.), d , Representative images show assessment of hind-limb clasping phenotype in hLGMN overexpressing mice and age-matched non-injected Grn ko mice (n=6 mice per condition). The clasping phenotype was quantified (n=6 mice per condition, mean ± s.e.m.). e , Longitudinal rotarod performance of Grn ko mice overexpressing hLGMN and age-matched controls (n=6 for Grn ko + hLGMN, n=6 for Grn ko control mice, mean ± s.e.m., multiple t-tests with FDR correction). f , Plasma NfL levels were measured before injection,1.5 months p.i and terminally. (n=6, mean ± s.d.).

Article Snippet: The AAV-PhP.eB-CAG- hLGMN vector used in this study was produced under research-grade conditions at SignaGen by triple transfection of adherent HEK293T cells.

Techniques: Western Blot, Injection, Expressing, In Vitro, Activity Assay

a , Immunofluorescence staining of sagittal brain sections 3 months post tail vein injection of AAV-PHP.eB.CAG-hLGMN (DAPI in blue, hLGMN in cyan, n=3 mice, scale bar = 1500 μm). b , Immunofluorescence staining for neuronal marker MAP2 (magenta), microglial marker IBA1 (orange) or astrocytic marker GFAP (yellow) and DAPI (blue). White arrowheads show co-localization of hLGMN with astrocytes, green arrowheads co-localization of hLGMN with microglia. (n=3 mice, scale bar = 20 μm).

Journal: bioRxiv

Article Title: Enhanced legumain activity links progranulin deficiency to TDP-43 pathology in frontotemporal lobar degeneration

doi: 10.1101/2024.01.16.575687

Figure Lengend Snippet: a , Immunofluorescence staining of sagittal brain sections 3 months post tail vein injection of AAV-PHP.eB.CAG-hLGMN (DAPI in blue, hLGMN in cyan, n=3 mice, scale bar = 1500 μm). b , Immunofluorescence staining for neuronal marker MAP2 (magenta), microglial marker IBA1 (orange) or astrocytic marker GFAP (yellow) and DAPI (blue). White arrowheads show co-localization of hLGMN with astrocytes, green arrowheads co-localization of hLGMN with microglia. (n=3 mice, scale bar = 20 μm).

Article Snippet: The AAV-PhP.eB-CAG- hLGMN vector used in this study was produced under research-grade conditions at SignaGen by triple transfection of adherent HEK293T cells.

Techniques: Immunofluorescence, Staining, Injection, Marker